Sodium Dithionite → HCID 135583121, compound

HRID 1253009Notes

Reaction equation

HRID 1253009 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[C:8]([C:15]=1[OH:16])=[CH:9][CH:10]=[CH:11][C:12](=[O:14])[N:13]=2)([O-])=O.S(S([O-])=O)([O-])=O.[Na+].[Na+]>O>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]2[C:8]([C:15]=1[OH:16])=[CH:9][CH:10]=[CH:11][C:12](=[O:14])[N:13]=2

Participants

4

Reactant 2

HCID 24489Sodium DithioniteHCID 135583126HCID 135583126, compound

Product 1

HCID 135583121HCID 135583121, compoundYield 66.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

7 g of the resulting 7-nitro-6-hydroxybenzazepin-2-one was dispersed in 50 ml of water, and to the dispersion was slowly added 30 g of sodium hydrosulfite while heating on a steam bath. After refluxing, the reaction mixture was cooled and the precipitated crystals were collected by filtration and dried to obtain 4 g of 7-amino-6-hydroxybenzazepin-2-one.

Workup

  1. temperaturewhile heating on a steam bath
  2. temperatureAfter refluxing
  3. temperaturethe reaction mixture was cooled
  4. filtrationthe precipitated crystals were collected by filtration
  5. customdried

Sources & evidence

ORD record
ord-986ff9a085a0462c85da1f6d859727d6
Source dataset
uspto-grants-1988_05
Patent number
US04746602

Reaction notes

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