Oxalic Acid → HCID 20138059, compound

HRID 1253023Notes

Reaction equation

HRID 1253023 reaction equation
[Cl:1][C:2]1[CH:12]=[N:11][C:10]2[CH2:9][CH:8]([CH2:13][CH2:14]Cl)[CH2:7][N:6]([CH3:16])[C:5](=[O:17])[C:4]=2[CH:3]=1.[NH:18]1[CH2:21][CH2:20][CH2:19]1.[C:22]([OH:27])(=[O:26])[C:23]([OH:25])=[O:24]>>[C:22]([OH:27])(=[O:26])[C:23]([OH:25])=[O:24].[N:18]1([CH2:14][CH2:13][CH:8]2[CH2:7][N:6]([CH3:16])[C:5](=[O:17])[C:4]3[CH:3]=[C:2]([Cl:1])[CH:12]=[N:11][C:10]=3[CH2:9]2)[CH2:21][CH2:20][CH2:19]1

Participants

4

Reactant 3

HCID 971Oxalic AcidHCID 10422AzetidineHCID 20138165HCID 20138165, compound

Product 1

HCID 20138059HCID 20138059, compound

Procedure

Following the procedure of Example 21, 3-chloro-8-(2-chloroethyl)-6,7,8,9-tetrahydro-6-methyl-5H-pyrido[3,2-c]azepin-5-one and azetidine are reacted and the free base of the title is isolated and reacted with oxalic acid.

Workup

  1. customare reacted
  2. customthe free base of the title is isolated

Sources & evidence

ORD record
ord-dcb9ccf586f545e498bb5091171232d6
Source dataset
uspto-grants-1988_05
Patent number
US04746657

Reaction notes

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