Hydrogen Sulfide → HCID 54241450, compound

Participants

Reaction Steps

2-Cyanomethylimidazole (0.83 g, 7.7 mmole) in 20 ml of dry pyridine was added to a medium pressure glass tube and was bubbled with hydrogen sulfide gas for 10 minutes. Then 1.5 equivalents of triethylamine (1.1 ml) was added. The tube was sealed and heated in a steam bath for 4 hours. The pressure tube was cooled and the excess hydrogen sulfide vented. Pyridine was removed under reduced pressure. Recrystallization from ethyl acetate-hexane afforded 0.42 gm of 2-thioacetamidoimidazole. m.p. 174° C. (decomposition).

Provenance & Evidence