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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1253165Generated: October 25, 2026

Ammonium Chloride → 5-(4-[2-Propylguanidino]pyrimid-2-yl)valeramidine hydrochloride

https://huagongshe.com/reaction/1253165

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium ChlorideHCID 25517—
ReactantMethyl 5-(4-[2-propylguanidino]pyrimid-2-yl)valerimidateHCID 20137162—
SolventMethanolHCID 887—
Product5-(4-[2-Propylguanidino]pyrimid-2-yl)valeramidine hydrochlorideHCID 2013714993.2%

Reaction Steps

A mixture of methyl 5-(4-[2-propylguanidino]pyrimid-2-yl)valerimidate (0.4 g.) and ammonium chloride (0.076 g.) in MeOH (20 ml.) was stirred at ambient temperature for 1 hour and the solvent evaporated in vacuo to give 5-(4-[2-propylguanidino]pyrimid-2-yl)valeramidine hydrochloride (0.4 g.) as an oil which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04748165
Source datasetuspto-grants-1988_05
ORD IDord-9f68561694d34a0d9c0e9e77265079fc
Source noteuspto-grants-1988_05