HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 135464214, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 2-Amino-9-[(4-chlorophenyl)methyl]-3,9-dihydro-6H-purin-6-one | HCID 135431360 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 135464214 | HCID 135464214 | — |
Reaction Steps
N-Bromosuccinimide (1.3 g, 7.3 mmol) is added to a suspension of 9-(4-chlorophenyl)methylguanine (1.5 g; 5.4 mmol), Example 3, in glacial acetic acid (100 ml) and the mixture is stirred for 20 hours at room temperature. The solution is poured into water (400 ml) and the resulting precipitate is filtered, washed with water and methanol and dried. Yield: 1.0 g; mp>300° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04748177 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-afce798328d84fc6b5c1c470fa917d36 |
| Source note | uspto-grants-1988_05 |