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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1253213Generated: October 29, 2026

1,3-Dihydro-5-(hydroxymethyl)-2H-benzimidazol-2-one → 1H-Benzimidazole-5-carboxaldehyde,2,3-dihydro-2-oxo-(9CI)

https://huagongshe.com/reaction/1253213

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Dihydro-5-(hydroxymethyl)-2H-benzimidazol-2-oneHCID 14518358—
CatalystHCID 178418406HCID 178418406—
SolventDimethylformamideHCID 6228—
Product1H-Benzimidazole-5-carboxaldehyde,2,3-dihydro-2-oxo-(9CI)HCID 23004148—

Reaction Steps

25.7 g (0.157 mol) of 20b in DMF are stirred with 81.7 g (0.939 mol) of manganese(IV) oxide for 2 days in analogy to Example 8b.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04748163
Source datasetuspto-grants-1988_05
ORD IDord-6b0b23a2f33b4a9c86bfec6690854e74
Source noteuspto-grants-1988_05