Sodium Cyanide → HCID 19894986, compound

HRID 1253214Notes

Reaction equation

[O:1]=[C:2]1[NH:6][C:5]2[CH:7]=[CH:8][C:9]([CH:11]=O)=[CH:10][C:4]=2[NH:3]1.[C:13](=[O:16])([O-])[O-].[NH4+:17].[NH4+:18].[C-]#N.[Na+].[CH3:22][OH:23].O>>[O:1]=[C:2]1[NH:6][C:5]2[CH:7]=[CH:8][C:9]([CH:11]3[NH:18][C:22](=[O:23])[NH:17][C:13]3=[O:16])=[CH:10][C:4]=2[NH:3]1

Participants

Reactant 4

HCID 8929Sodium Cyanide

HCID 517111Ammonium Carbonate

HCID 22242641Methanol--water (1/1)

HCID 230041481H-Benzimidazole-5-carboxaldehyde,2,3-dihydro-2-oxo-(9CI)

Product 1

HCID 19894986HCID 19894986, compound

Procedure

10.7 g (0.0659 mol) of 20c in methanol/water are reacted with 27.8 mol) of ammonium carbonate and 5.2 g (0.107 mol) of sodium cyanide in analogy to Example 1c.

Sources & evidence

ORD record: ord-77fbab5aa43347d1bb3fade2c348e46c
Source dataset: uspto-grants-1988_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04748163

Reaction notes

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