Potassium Cation → 5-(1-benzhydryl-4-hydroxypyrrolidin-2-yl)-4-[(3,5-difluorophenyl)methyl]-1,3-oxazolidin-2-one
Reaction equation
[Br:106][CH:107]([c:108]1[cH:109][cH:110][cH:111][cH:112][cH:113]1)[c:114]1[cH:115][cH:116][cH:117][cH:118][cH:119]1.[C:100](=[O:101])([O-:102])[O-:103].[CH3:120][C:121]#[N:122].[F:1][c:2]1[cH:3][c:4]([CH2:9][CH:10]2[CH:11]([CH:12]3[CH2:13][CH2:14][CH2:15][CH2:16][N:17]3[CH:18]([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[O:31][C:32](=[O:33])[NH:34]2)[cH:5][c:6]([F:7])[cH:8]1.[F:35][c:36]1[cH:37][c:38]([CH2:39][CH:40]2[NH:41][C:42](=[O:64])[O:43][CH:44]2[CH:45]2[CH2:46][O:47][CH2:48][CH2:49][N:50]2[CH:51]([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[cH:65][c:66]([F:68])[cH:67]1.[F:69][c:70]1[cH:71][c:72]([CH2:77][CH:78]([CH:79]([CH:80]2[CH2:81][CH:82]([O:83][CH2:84][CH:85]=[CH2:86])[CH2:87][N:88]2[C:89]([O:90][C:91]([CH3:92])([CH3:93])[CH3:94])=[O:95])[OH:96])[C:97]([OH:98])=[O:99])[cH:73][c:74]([F:75])[cH:76]1.[K+:104].[K+:105]>>[F:35][c:36]1[cH:37][c:38]([CH2:39][CH:40]2[NH:41][C:42](=[O:64])[O:43][CH:44]2[CH:45]2[CH2:46][CH:48]([OH:47])[CH2:49][N:50]2[CH:51]([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[cH:65][c:66]([F:68])[cH:67]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e59aad6666fd460b9a026e9bc7433921
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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