HCID 15611125, compound → HCID 15611126, compound

Participants

Reaction Steps

A mixture of 5 g of Ethyl 2-(4-acetyl-2-n-propyl-3-hydroxyphenoxy)-2-(4-chlorophenyl)acetate in 100 ml of dioxane and 15 ml of concentrated hydrochloric acid was refluxed for 70 hours. The reaction mixture was then cooled and concentrated in vacuum to give 2.6 g of the crude solid. The crude product was crystallized from EtOAc/hexane to give 1.5 g of the pure product, melting point 163°-164°.

Provenance & Evidence