HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfoxide → p-Methylcinnamaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Methylcinnamyl alcohol | HCID 5387482 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | p-Methylcinnamaldehyde | HCID 5371802 | — |
Reaction Steps
Following General Procedure H, oxalyl chloride (7.1 ml, 14.2 mmol, 2 M in CH2Cl2), DMSO (1.3 ml, 18.9 mmol), (E)-3-(4-methylphenyl)prop-2-en-1-ol (Compound 41, 1.4 g, 9.5 mmol) and triethylamine (4.4 ml, 31.4 mmol) in CH2Cl2 (5 ml) were reacted to obtain the title compound as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728014B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-ff46d30221ab41f09c751f2de95c3f11 |
| Source note | uspto-grants-2010_06 |