Phenylhydrazine → HCID 67207603, compound

Participants

Reaction Conditions

Reaction Steps

Methyl (2Z)-2-[(dimethylamino)methylene]-3-oxopentanoate (383 mg, 2.07 mmol) and phenylhydrazine (0.308 ml, 3.10 mmol) were added to ethanol (4 ml). The reaction mixture was heated to 150° C. in the Biotage Initiator Series microwave. After 30 minutes, the reaction mixture was cooled and concentrated. The residue was purified by column chromatography on silica gel (ethyl acetate/hexanes gradient) to afford methyl 5-ethyl-1-phenyl-1H-pyrazole-4-carboxylate.

Provenance & Evidence