HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic acid, azido-, ethyl ester → Ethyl (2Z,4E)-2-azido-5-(4-methylphenyl)penta-2,4-dienoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic acid, azido-, ethyl ester | HCID 69480 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | p-Methylcinnamaldehyde | HCID 5371802 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl (2Z,4E)-2-azido-5-(4-methylphenyl)penta-2,4-dienoate | HCID 12378027 | — |
Reaction Steps
Following General Procedure I, a 1.38 M solution of NaOEt in ethanol (30 ml), (E)-3-(4-methylphenyl)acrylaldehyde (Compound 43, 1.1 g, 7.5 mmol) and ethyl azidoacetate (12 ml, 37.5 mmol) in EtOH (20 ml) were reacted to produce the title compound as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728014B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-b4766f87ad664e35965873e1b072eb02 |
| Source note | uspto-grants-2010_06 |