HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1253507Generated: November 1, 2026
HCID 178471941, compound → Ethyl 4-hydroxy-3,4-dihydro-1,5-naphthyridine-3-carboxylate
https://huagongshe.com/reaction/1253507
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 178471941 | HCID 178471941 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | Ethyl 4-hydroxy-3,4-dihydro-1,5-naphthyridine-3-carboxylate | HCID 67207071 | — |
Reaction Steps
Diethyl [(E)-(pyridin-3-ylimino)methyl]malonate (9 g, 34 mmol) was dissolved in 1,1′-oxydibenzene (150 ml). The mixture was heated at 250° C. for 2 hours, and then cooled to room temperature. The reaction mixture was filtered to give ethyl 4-hydroxy-3,4-dihydro-1,5-naphthyridine-3-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08455477B2 |
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| Source dataset | uspto-grants-2013_06 |
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| ORD ID | ord-c8cab84f26644dd2b6cbc67822f071e7 |
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| Source note | uspto-grants-2013_06 |
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