HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl-3-(2-ethoxy-2-oxoethylidene)pyrrolidine-1-carboxylate → tert-Butyl 3-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl-3-(2-ethoxy-2-oxoethylidene)pyrrolidine-1-carboxylate | HCID 67205087 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | tert-Butyl 3-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate | HCID 15384752 | — |
Reaction Steps
A flask was charged with EtOH (700 ml), tert-butyl 3-(2-ethoxy-2-oxoethylidene)pyrrolidine-1-carboxylate (246 g, 965 mmol) and Pd/C (40 g). Then the flask was charged with H2 (3 L). The resulting solution was stirred overnight. The reaction mixture was filtered and concentrated to afford tert-butyl 3-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455477B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-4ab1f571054840fe81fa465cae412560 |
| Source note | uspto-grants-2013_06 |