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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1253622Generated: November 3, 2026

1-Methyl-3-aminopyrazole → N,N-dimethyl-5-(2-methyl-6-((1-methyl-1H-pyrazol-3-yl)-carbamoyl)benzofuran-4-yloxy)pyrimidine-2-carboxamide

https://huagongshe.com/reaction/1253622

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-3-aminopyrazoleHCID 137254—
ReactantEthyl 4-(2-(dimethylcarbamoyl)pyrimidin-5-yloxy)-2-methylbenzofuran-6-carboxylateHCID 59483316—
ProductN,N-dimethyl-5-(2-methyl-6-((1-methyl-1H-pyrazol-3-yl)-carbamoyl)benzofuran-4-yloxy)pyrimidine-2-carboxamideHCID 46916695—

Reaction Steps

The title compound (4) was prepared by a method analogous to that described in Example 1 using 1-methyl-1H-pyrazol-3-amine and ethyl 4-(2-(dimethylcarbamoyl)pyrimidin-5-yloxy)-2-methylbenzofuran-6-carboxylate (I-2a)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455496B2
Source datasetuspto-grants-2013_06
ORD IDord-fa0aa0bfd23d4d6cb5c62d940892d071
Source noteuspto-grants-2013_06