Toluene → 4-Methyl-2-{1-[6-trifluoromethyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-1H-imidazol-4-yl}-thiazole-5-sulfonic acid tert-butylamide
Reaction equation
[C:39]([CH3:40])([CH3:41])([CH3:42])[NH:43][S:44](=[O:45])(=[O:46])[c:47]1[c:48]([CH3:53])[n:49][c:50]([Cl:52])[s:51]1.[CH2:1]([Sn:2]([CH2:3][CH2:4][CH2:5][CH3:31])([c:6]1[n:7][cH:8][n:9](-[c:11]2[n:12][c:13]([C:27]([F:28])([F:29])[F:30])[cH:14][c:15](-[c:17]3[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]3)[cH:16]2)[cH:10]1)[CH2:32][CH2:33][CH2:34][CH3:35])[CH2:36][CH2:37][CH3:38].[CH3:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH3:60].[CH3:61][c:62]1[cH:63][cH:64][cH:65][cH:66][cH:67]1>>[c:6]1(-[c:50]2[n:49][c:48]([CH3:53])[c:47]([S:44]([NH:43][C:39]([CH3:40])([CH3:41])[CH3:42])(=[O:45])=[O:46])[s:51]2)[n:7][cH:8][n:9](-[c:11]2[n:12][c:13]([C:27]([F:28])([F:29])[F:30])[cH:14][c:15](-[c:17]3[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]3)[cH:16]2)[cH:10]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-bad3eb7daedf4cf28c035189c9af9cab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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