5-Methoxynicotinic acid → N-[5-Cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-5-methoxy-nicotinamide

Participants

Reaction Steps

This compound was prepared following the same procedure as described for Example 3 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (Example 1c) (100 mg, 0.33 mmol) and 5-methoxy-nicotinic acid (50.49 mg, 0.33 mmol) as starting materials. The title compound (73 mg, 48.2%) was isolated as off white solid; MS (ESI): 396 [M+H]+.

Provenance & Evidence