5-Cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine → 5-methyl-2H-pyrazole-3-carboxylic acid [5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-amide

Participants

Reaction Steps

This compound was prepared following the same procedure as described for Example 3 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (Example 1c) (100 mg, 0.33 mmol) and 5-methyl-2H-pyrazole-3-carboxylic acid (41.6 mg, 0.33 mmol) as starting materials. The title compound (33 mg, 23.4%) was isolated as off white solid; MS (ESI): 369 [M+H]+.

Provenance & Evidence