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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1253783Generated: October 26, 2026

Benzoic Acid → N-[5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-benzamide

https://huagongshe.com/reaction/1253783

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic AcidHCID 243—
Reactant5-Cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamineHCID 71294172—
ProductN-[5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-benzamideHCID 7129427757.4%

Reaction Steps

This compound was prepared following the same procedure as described for Example 3 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (Example 1c) (100 mg, 0.38 mmol) and benzoic acid (40 mg, 0.33 mmol) as starting materials. The title compound (69 mg, 49.3%) was isolated as off white solid; MS (ESI): 365 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455501B2
Source datasetuspto-grants-2013_06
ORD IDord-a34e7e881f134b60a1eda9ced9976b2e
Source noteuspto-grants-2013_06