HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic Acid → N-[5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic Acid | HCID 243 | — |
| Reactant | 5-Cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine | HCID 71294172 | — |
| Product | N-[5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-benzamide | HCID 71294277 | 57.4% |
Reaction Steps
This compound was prepared following the same procedure as described for Example 3 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (Example 1c) (100 mg, 0.38 mmol) and benzoic acid (40 mg, 0.33 mmol) as starting materials. The title compound (69 mg, 49.3%) was isolated as off white solid; MS (ESI): 365 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455501B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-a34e7e881f134b60a1eda9ced9976b2e |
| Source note | uspto-grants-2013_06 |