Pyrimidine-5-carboxylic acid → Pyrimidine-5-carboxylic acid [5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-amide

Beteiligte Stoffe

Reaktionsschritte

This compound was prepared following the same procedure as described for Example 3 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (Example 1c) (100 mg, 0.38 mmol) and pyrimidine-5-carboxylic acid (41 mg, 0.33 mmol) as starting materials. The title compound (23 mg, 15.7%) was isolated as off white solid; MS (ESI): 367 [M+H]+.

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