HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-4-[(4-methylbenzenesulfonyl)oxy]butan-2-ol → 4-(5-Bromo-4,6-dimethylpyridin-2-yloxy)-2-methylbutan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-4-[(4-methylbenzenesulfonyl)oxy]butan-2-ol | HCID 14001295 | — |
| Reactant | HCID 178429301 | HCID 178429301 | — |
| Product | 4-(5-Bromo-4,6-dimethylpyridin-2-yloxy)-2-methylbutan-2-ol | HCID 59544534 | 70.1% |
Reaction Steps
According to a method described in [WO 2009/054423 pamphlet, (Production Example 37)], from 5-bromo-4,6-dimethyl-2-hydroxypyridine (1.50 g) and 3-hydroxy-3-methylbutyl 4-methylbenzenesulfonate (2.11 g), the subject compound (1.50 g) was obtained as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455500B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-743b476f845d4cebb8691bd3a5e7e018 |
| Source note | uspto-grants-2013_06 |