Ethyl propiolate → HCID 55253267, compound

HRID 1253801Notes

Reaction equation

I[C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.[C:9]([O:13][CH2:14][CH3:15])(=[O:12])[C:10]#[CH:11]>>[OH:8][C:4]1[CH:3]=[C:2]([C:11]#[C:10][C:9]([O:13][CH2:14][CH3:15])=[O:12])[CH:7]=[CH:6][CH:5]=1

Participants

Reactant 2

HCID 12182Ethyl propiolate

HCID 122723-Iodophenol

Product 1

HCID 55253267HCID 55253267, compoundYield 73.1%

Procedure

According to the method of (Reference Example 3), from 3-iodophenol (1.18 g) and ethyl propiolate (1.0 g), the subject compound (746 mg) was obtained as a yellow solid.

Sources & evidence

ORD record: ord-3d7c828984bb4f8f91638f9dfc5fbc74
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08455500B2

Reaction notes

Loading…