2-Methyl-4-[(4-methylbenzenesulfonyl)oxy]butan-2-ol → HCID 68193930, compound

HRID 1253806Notes

Reaction equation

HRID 1253806 reaction equation
[Br:1][C:2]1[C:3]([CH3:10])=[C:4]([CH3:9])[C:5]([OH:8])=[N:6][CH:7]=1.CC1C=CC(S(O[CH2:22][CH2:23][C:24]([OH:27])([CH3:26])[CH3:25])(=O)=O)=CC=1>>[Br:1][C:2]1[C:3]([CH3:10])=[C:4]([CH3:9])[C:5]([O:8][CH2:22][CH2:23][C:24]([CH3:26])([OH:27])[CH3:25])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 140012952-Methyl-4-[(4-methylbenzenesulfonyl)oxy]butan-2-olHCID 178421703HCID 178421703, compound

Product 1

HCID 68193930HCID 68193930, compoundYield 49.1%

Procedure

According to the method of (Example 36) <Step 1>, from 5-bromo-3,4-dimethylpyridin-2-ol (3.0 g) and 3-hydroxy-3-methylbutyl 4-methylbenzenesulfonate (4.2 g), the subject compound (2.1 g) was obtained as a white solid.

Sources & evidence

ORD record
ord-ba72d94d7963431fb2906229b41a3326
Source dataset
uspto-grants-2013_06
Patent number
US08455500B2

Reaction notes

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