Hydrazine → HCID 66986330, compound

Participants

Reaction Steps

Methyl 4-(5-iodo-1-methyl-2-pyridin-2-yl-1H-imidazol-4-yl)benzoate (Step 3, 2 g, 1.9 mmol) was suspended in 10 mL of EtOH and 3 mL of anhydrous hydrazine, and heated at reflux for 2 h. After the reaction was cooled to rt, the solid product was filtered, washed with hexanes, and air-dried to give 750 mg of 4-(5-iodo-1-methyl-2-pyridin-2-yl-1H-imidazol-4-yl)benzohydrazide. LCMS: [M+1]=420.

Provenance & Evidence