Acetic Acid → HCID 44553896, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of the crude product of Step 1, 2 mL of acetic acid and 0.15 mL of anhydrous hydrazine was stirred at 90° C. for 30 min. The reaction mixture was diluted with MeOH and was purified by reverse phase HPLC to afford the title compound. 1H NMR (500 MHz, (CD3OD): 8.08 (s, 1H), 8.05 (m, 4H), 7.73 (m, 2H), 7.58 (m, 3H), 7.35 (d, 2H), 7.11 (d, 2H), 3.68 (s, 3H), 1.61 (s, 6H). LCMS: m/z 421 (M+H)+.

Provenance & Evidence