Methyl iodide → HCID 44553732, compound

Participants

Reaction Steps

To the product of Step 1 in 1.5 mL of DMF was added K2CO3 (85 mg, 0.61 mmol). After stirring at rt for 30 min, MeI (0.05 mL, 0.82 mmol) was added and stirring continued for 1.5 h. The reaction mixture was diluted with MeOH/MeCN, and the precipitate was collected by filtration to give the title compound. 1H NMR (500 MHz, (CDCl3): 8.44 (d, 1H), 8.39 (d, 1H), 8.27 (d, 2H), 8.19 (d, 2H), 7.88 (t, 1H), 7.36 (dd, 1H), 7.26 (d, 2H), 7.07 (d, 2H), 4.42 (s, 3H), 4.15 (s, 3H). LCMS: m/z 460 (M+H)+.

Provenance & Evidence