Water → HCID 24946152, compound

Participants

Reaction Steps

The solution containing 590 mg of 5-(2-methoxy-ethyl)-2-(3-methoxy-4-methoxymethoxy-phenyl)-3-methylsulfanyl-benzofuran (14a; 1.52 mM) dissolved in 8 ml of dichloromethane was cooled to 0□. 4.0 ml of trifluoroacetic acid was added thereto and stirred for 40 mins at 0□. 7.5 g of solid sodium hydrogen carbonate and 60 ml of water were added thereto slowly at 0□. The reaction mixture was extracted with dichloromethane. The organic solvent layer was dried with magnesium sulfuric acid, filtrated and the filtrate was concentrated with vaccuo.

Provenance & Evidence