HCID 57845584, compound → HCID 57814829, compound

Participants

Reaction Steps

A solution of 1 g (2.49 mmol) of alcohol 4 in 13 mL of EtOAc and Adam's catalyst (22 mg) was stirred under 30 psi of hydrogen gas in a Parr apparatus over 21 h. The mixture was then filtered to remove the catalyst through a plug of silica gel with EtOAc as solvent. The filtrate was then concentrated in vacuo yield the propyl ester 11 (990 mg) as an oil; 1H NMR (CDCl3); 0.94 (t, J=7.3 Hz, 3H), 1.20-1.94 (m, 31H), 2.17 (m, 2H), 2.32 (m, 4H), 3.46-4.12 (m, 8H), 4.03 (t, J=6.6 Hz, 2H), 4.13-4.38 (m, 2H), 4.59 (m, 1H), 4.73 (m, 1H).

Provenance & Evidence