Acetate → Tert-butyl 2-((2,3-dihydrobenzo[1,4]dioxin-6-yl)amino)-4-phenylbenzoate

HRID 125441Notes

Reaction equation

HRID 125441 reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[C:38]([O-:39])(=[O:40])[CH3:41].[C:43]([O-:44])(=[O:45])[CH3:46].[CH3:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1.[Cs+:25].[Cs+:26].[I:27][c:28]1[cH:29][c:30]2[c:31]([cH:36][cH:37]1)[O:32][CH2:33][CH2:34][O:35]2.[NH2:1][c:2]1[c:3]([C:4](=[O:5])[O:6][C:7]([CH3:8])([CH3:9])[CH3:10])[cH:11][cH:12][c:13](-[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:14]1.[Pd+2:42]>>[NH:1]([c:2]1[c:3]([C:4](=[O:5])[O:6][C:7]([CH3:8])([CH3:9])[CH3:10])[cH:11][cH:12][c:13](-[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:14]1)[c:28]1[cH:29][c:30]2[c:31]([cH:36][cH:37]1)[O:32][CH2:33][CH2:34][O:35]2

Participants

8

Reactant 7

HCID 175Acetate2×HCID 1140TolueneHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 27761766-Iodo-2,3-dihydro-1,4-benzodioxineHCID 58508425Tert-butyl 3-amino-[1,1'-biphenyl]-4-carboxylate

Product 1

HCID 68959355Tert-butyl 2-((2,3-dihydrobenzo[1,4]dioxin-6-yl)amino)-4-phenylbenzoate

Sources & evidence

ORD record
ord-f6cdf337325c439c9ddda4d2ebdc0c07
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…