HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Quinolinecarboxaldehyde → (S)-1,1-diethoxy-N-(quinolin-8-ylmethyl)propan-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Quinolinecarboxaldehyde | HCID 170103 | — |
| Reactant | (2S)-1,1-Diethoxy-2-propanamine | HCID 12398111 | — |
| Product | (S)-1,1-diethoxy-N-(quinolin-8-ylmethyl)propan-2-amine | HCID 67074994 | 91% |
Reaction Steps
According to the procedure described in the synthesis method of Compound IX-2, (S)-1,1-diethoxypropan-2-amine (Compound XIX-1) 442 mg (3.00 mmol) was reacted with 8-Quinolinecarboaldehyde 393 mg (2.50 mmol) to obtain the title compound 649 mg (91%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455488B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-5226196d7bce46eabff41d370d3ae27c |
| Source note | uspto-grants-2013_06 |