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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1254535Generated: October 27, 2026

2-(1-Methyl-2-((pyridin-4-ylmethyl)carbamoyl)hydrazinyl)acetic acid → HCID 86698536, compound

https://huagongshe.com/reaction/1254535

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-Methyl-2-((pyridin-4-ylmethyl)carbamoyl)hydrazinyl)acetic acidHCID 53397520—
Reactanttert-butyl (S)-5-amino-6-(((S)-1,1-diethoxypropan-2-yl)(naphthalen-1-ylmethyl)amino)-6-oxohexylcarbamateHCID 86698537—
ProductHCID 86698536HCID 86698536—

Reaction Steps

According to the procedure described in the synthesis method of Compound II-15, 2-(1-methyl-2-(pyridin-4-ylmethylcarbamoyl)hydrazinyl)acetic acid (Compound VI-6) 69 mg (0.29 mmol) was coupled with tert-butyl (S)-5-amino-6-(((S)-1,1-diethoxypropan-2-yl)-(naphthalen-1-ylmethyl)amino)-6-oxohexylcarbamate (Compound IV-13) 100 mg (0.19 mmol) to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455488B2
Source datasetuspto-grants-2013_06
ORD IDord-30f0921309574d90a7932a85bbc24596
Source noteuspto-grants-2013_06