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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1254539Generated: October 30, 2026

2-(1-Methyl-2-((pyridin-4-ylmethyl)carbamoyl)hydrazinyl)acetic acid → HCID 67088422, compound

https://huagongshe.com/reaction/1254539

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-Methyl-2-((pyridin-4-ylmethyl)carbamoyl)hydrazinyl)acetic acidHCID 53397520—
Reactant(S)-tert-butyl 3-amino-4-(((S)-1,1-diethoxypropan-2-yl)(naphthalen-1-ylmethyl)amino)-4-oxobutanoateHCID 67075348—
ProductHCID 67088422HCID 67088422—

Reaction Steps

According to the procedure described in the synthesis method of Compound II-15, 2-(1-methyl-2-(pyridin-4-ylmethylcarbamoyl)hydrazinyl)acetic acid (Compound VI-6) 78 mg (0.33 mmol) was coupled with (S)-tert-butyl 3-amino-4-(((S)-1,1-diethoxypropan-2-yl)-(naphthalen-1-ylmethyl)amino)-4-oxobutanoate IV-16) 100 mg (0.22 mmol) to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455488B2
Source datasetuspto-grants-2013_06
ORD IDord-3041065686d24e47bf18e15dcb9399eb
Source noteuspto-grants-2013_06