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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1254567Generated: October 31, 2026

2-(1-Methyl-2-((naphthalen-1-ylmethyl)carbamoyl)hydrazinyl)acetic acid → HCID 67075467, compound

https://huagongshe.com/reaction/1254567

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-Methyl-2-((naphthalen-1-ylmethyl)carbamoyl)hydrazinyl)acetic acidHCID 53397539—
Reactant(S)-2-amino-N-(benzo[b]thiophen-3-ylmethyl)-N-((S)-1,1-diethoxypropan-2-yl)propanamideHCID 67075261—
ProductHCID 67075467HCID 67075467—

Reaction Steps

According to the procedure described in the synthesis method of Compound II-15, 2-(1-methyl-2-(naphthalen-1-ylmethylcarbamoyl)hydrazinyl)acetic acid (Compound VI-8) 118 mg (0.41 mmol) was coupled with (S)-2-amino-N-(benzo[b]thiophen-3-ylmethyl)-N—((S)-1,1-diethoxypropan-2-yl)propanamide (Compound IV-12) 100 mg (0.27 mmol) to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455488B2
Source datasetuspto-grants-2013_06
ORD IDord-ae38b81d9a9e47fe9409dd647617244a
Source noteuspto-grants-2013_06