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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1254581Generated: November 2, 2026

2-(1-Methyl-2-((naphthalen-1-ylmethyl)carbamoyl)hydrazinyl)acetic acid → HCID 86652588, compound

https://huagongshe.com/reaction/1254581

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-Methyl-2-((naphthalen-1-ylmethyl)carbamoyl)hydrazinyl)acetic acidHCID 53397539—
Reactant(S)-2-amino-N1-(benzo[b]thiophen-3-ylmethyl)-N1-((S)-1,1-diethoxy-propan-2-yl)-N4-tritylsuccinamideHCID 67075021—
ProductHCID 86652588HCID 86652588—

Reaction Steps

According to the procedure described in the synthesis method of Compound II-15, 2-(1-methyl-2-(naphthalen-1-ylmethylcarbamoyl)hydrazinyl)acetic acid (Compound VI-8) 66 mg (0.23 mmol) was coupled with (S)-2-amino-N1-(benzo[b]thiophen-3-ylmethyl)-N1—((S)-1,1-diethoxypropan-2-yl)-N4-tritylsuccinamide (Compound IV-21) 100 mg (0.15 mmol) to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455488B2
Source datasetuspto-grants-2013_06
ORD IDord-27495173e4de492b973f332bf148a1e8
Source noteuspto-grants-2013_06