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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1254590Generated: November 1, 2026

2-(3-(Naphthalen-1-ylmethyl)ureidooxy)acetic acid → HCID 86652596, compound

https://huagongshe.com/reaction/1254590

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-(Naphthalen-1-ylmethyl)ureidooxy)acetic acidHCID 53397538—
Reactant(S)-2-amino-3-(4-tert-butoxyphenyl)-N-((S)-1,1-diethoxypropan-2-yl)-N-(naphthalen-1-ylmethyl)propanamideHCID 67075242—
ProductHCID 86652596HCID 86652596—

Reaction Steps

According to the procedure described in the synthesis method of Compound II-15, 2-(3-(naphthalen-1-ylmethyl)ureidooxy)acetic acid (Compound VI-12) 81 mg (0.30 mmol) was coupled with (S)-2-amino-3-(4-tert-butoxyphenyl)-N—((S)-1,1-diethoxypropan-2-yl)-N-(naphthalen-1-ylmethyl)propanamide (Compound IV-2) 100 mg (0.20 mmol) to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455488B2
Source datasetuspto-grants-2013_06
ORD IDord-0d26272ba5ff4e248b934b1ccfdc494b
Source noteuspto-grants-2013_06