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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1254591Generated: October 28, 2026

2-(3-Ethylureidooxy)acetic acid → HCID 86652597, compound

https://huagongshe.com/reaction/1254591

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Ethylureidooxy)acetic acidHCID 53397416—
Reactant(S)-2-amino-3-(4-tert-butoxyphenyl)-N-((S)-1,1-diethoxypropan-2-yl)-N-(naphthalen-1-ylmethyl)propanamideHCID 67075242—
ProductHCID 86652597HCID 86652597—

Reaction Steps

According to the procedure described in the synthesis method of Compound II-15, 2-(3-ethylureidooxy)acetic acid (Compound VI-13) 48 mg (0.30 mmol) was coupled with (S)-2-amino-3-(4-tert-butoxyphenyl)-N—((S)-1,1-diethoxypropan-2-yl)-N-(naphthalen-1-ylmethyl)propanamide (Compound IV-2) 100 mg (0.20 mmol) to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455488B2
Source datasetuspto-grants-2013_06
ORD IDord-1e531e0799974ba085f52d24d7331e21
Source noteuspto-grants-2013_06