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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1254601Generated: October 31, 2026

2-(3-(4-Chlorobenzyl)ureidooxy)acetic acid → HCID 86652607, compound

https://huagongshe.com/reaction/1254601

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-(4-Chlorobenzyl)ureidooxy)acetic acidHCID 53397500—
Reactant(S)-2-amino-3-(4-tert-butoxyphenyl)-N-((S)-1,1-diethoxypropan-2-yl)-N-(quinolin-8-ylmethyl)propanamideHCID 67075208—
ProductHCID 86652607HCID 86652607—

Reaction Steps

According to the procedure described in the synthesis method of Compound II-15, 2-(3-(4-chlorobenzyl)ureidooxy)acetic acid (Compound VI-11) 76 mg (0.30 mmol) was coupled with (S)-2-amino-3-(4-tert-butoxyphenyl)-N—((S)-1,1-diethoxypropan-2-yl)-N-(quinolin-8-ylmethyl)propanamide (Compound IV-3) 100 mg (0.20 mmol) to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455488B2
Source datasetuspto-grants-2013_06
ORD IDord-3d17eed5e91e4ba2837ba52846ce3e03
Source noteuspto-grants-2013_06