HCID 24859298, compound → HCID 44469412, compound

HRID 1254817Notes

Reaction equation

HRID 1254817 reaction equation
Br[C:2]1[CH:11]=[C:10]2[C:5]([C:6]([NH:12][C:13]([NH:15][C:16]3[CH:21]=[N:20][CH:19]=[CH:18][N:17]=3)=[O:14])=[CH:7][CH:8]=[N:9]2)=[CH:4][CH:3]=1.[N:22]1([C:30]([O:32][C:33]([CH3:36])([CH3:35])[CH3:34])=[O:31])[CH:26]2[CH2:27][NH:28][CH2:29][CH:25]2[CH2:24][CH2:23]1>>[N:17]1[CH:18]=[CH:19][N:20]=[CH:21][C:16]=1[NH:15][C:13](=[O:14])[NH:12][C:6]1[C:5]2[C:10](=[CH:11][C:2]([N:28]3[CH2:29][CH:25]4[CH:26]([N:22]([C:30]([O:32][C:33]([CH3:36])([CH3:35])[CH3:34])=[O:31])[CH2:23][CH2:24]4)[CH2:27]3)=[CH:3][CH:4]=2)[N:9]=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 24859298HCID 24859298, compoundHCID 44474550tert-butyl hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate

Product 1

HCID 44469412HCID 44469412, compound

Procedure

The compound was prepared by the method described for Example 1 using 1-(7-bromoquinolin-4-yl)-3-(pyrazin-2-yl)urea and tert-butyl hexahydropyrrolo[2,3-c]pyrrole-1(2H)-carboxylate as starting compounds.

Workup

  1. customThe compound was prepared by the method

Sources & evidence

ORD record
ord-df14f63d0d3f465496d1b6fcafd2dcd0
Source dataset
uspto-grants-2013_06
Patent number
US08455648B2

Reaction notes

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