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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1254912Generated: October 26, 2026

3-Amino-4-chlorobenzonitrile → 2-Chloro-5-cyanobenzene-1-sulfonyl chloride

https://huagongshe.com/reaction/1254912

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-4-chlorobenzonitrileHCID 104464—
Reactant4-Fluoro-3-methoxybenzenesulfonyl chlorideHCID 2783408—
Product2-Chloro-5-cyanobenzene-1-sulfonyl chlorideHCID 53301994—

Reaction Steps

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 3-amino-4-chloro-benzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455645B2
Source datasetuspto-grants-2013_06
ORD IDord-85d1f019fac347b389775740cef6687b
Source noteuspto-grants-2013_06