4-Methoxy-3-nitrobenzonitrile → 5-Cyano-2-methoxybenzene-1-sulfonyl chloride

HRID 1254915Notes

Reaction equation

HRID 1254915 reaction equation
C(C1C=CC([S:9]([Cl:12])(=[O:11])=[O:10])=CC=1OCC)#N.[CH3:16][O:17][C:18]1[CH:25]=[CH:24][C:21]([C:22]#[N:23])=[CH:20][C:19]=1[N+]([O-])=O>>[C:22]([C:21]1[CH:24]=[CH:25][C:18]([O:17][CH3:16])=[C:19]([S:9]([Cl:12])(=[O:11])=[O:10])[CH:20]=1)#[N:23]

Participants

3

Reactant 2

HCID 28002414-Methoxy-3-nitrobenzonitrileHCID 552808794-Cyano-3-ethoxybenzene-1-sulfonyl chloride2×

Product 1

HCID 115287515-Cyano-2-methoxybenzene-1-sulfonyl chloride

Procedure

The titled compound was prepared analogously to 4-cyano-3-ethoxy-benzenesulfonyl chloride (Intermediate 127c) by replacing 2-ethoxy-4-nitro-benzonitrile with 4-methoxy-3-nitro-benzonitrile.

Sources & evidence

ORD record
ord-5d002379bb9a4aefae600f63c7dc6abd
Source dataset
uspto-grants-2013_06
Patent number
US08455645B2

Reaction notes

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