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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1254917Generated: November 3, 2026

6-Chloro-m-anisidine → 2-Chloro-5-methoxybenzene-1-sulfonyl chloride

https://huagongshe.com/reaction/1254917

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-m-anisidineHCID 75460—
Reactant4-Fluoro-3-methoxybenzenesulfonyl chlorideHCID 2783408—
Product2-Chloro-5-methoxybenzene-1-sulfonyl chlorideHCID 22033536—

Reaction Steps

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 2-chloro-5-methoxy-phenylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455645B2
Source datasetuspto-grants-2013_06
ORD IDord-c91fd2c2a30746a49e514c76afe019b9
Source noteuspto-grants-2013_06