HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-2-(trifluoromethyl)benzonitrile → 4-Cyano-3-(trifluoromethyl)benzene-1-sulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-2-(trifluoromethyl)benzonitrile | HCID 522170 | — |
| Reactant | 4-Fluoro-3-methoxybenzenesulfonyl chloride | HCID 2783408 | — |
| Product | 4-Cyano-3-(trifluoromethyl)benzene-1-sulfonyl chloride | HCID 54592428 | — |
Reaction Steps
The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 4-amino-2-trifluoromethyl-benzonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455645B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-cbc257b4500849a48929e96d4c9b89b4 |
| Source note | uspto-grants-2013_06 |