HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-methylbenzohydrazide → N-methylbenzoselenohydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-methylbenzohydrazide | HCID 242395 | — |
| Reactant | 2,4-Diphenyl-1,3,2,4-diselenadiphosphetane 2,4-diselenide | HCID 5066075 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-methylbenzoselenohydrazide | HCID 57551066 | 194.7% |
Reaction Steps
A mixture of N-methylbenzohydrazide (450 mg, 3.0 mmol) and the Woollins' Reagent (540 mg, 1 mmol) in anhydrous toluene (10 ml), was heated at 120° C. for 1 h. The resulting orange solution was cooled to room temperature, the solvent was removed in vacuo and the selenoamide purified by column chromatography on silica gel (3:1 Hexane:EtOAc) and to give N-methylbenzoselenohydrazide (415 mg) in 65% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455686B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-68089c19d2634c81b338150254dfd788 |
| Source note | uspto-grants-2013_06 |