反应详情

Into a solution of Compound 27 (21.0 mg, 0.05 mmol) in ethanol (2.0 mL) was added 10% Pd/C (10.0 mg). The mixture was stirred under 1 atmosphere of hydrogen for overnight. The mixture was filtered through a short plug of silica to give Compound 54, 19.4 mg, 92%) as a white solid.

1. filtrationThe mixture was filtered through a short plug of silica