HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → N-(5-(7-Bromobenzo[d][1,3]dioxol-5-yl)-4-methylthiazol-2-yl)-2,6-difluorobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Benzo[1,3]dioxol-5-yl-acetyl chloride | HCID 2756584 | — |
| Reactant | N-(5-(2,5-Dimethoxyphenyl)-4-methylthiazol-2-yl)-2,6-difluorobenzamide | HCID 24765404 | — |
| Product | N-(5-(7-Bromobenzo[d][1,3]dioxol-5-yl)-4-methylthiazol-2-yl)-2,6-difluorobenzamide | HCID 24765405 | — |
Reaction Steps
Compound 56 was prepared from 2-(benzo[d][1,3]dioxol-5-yl)acetyl chloride in the similar manner as described for the preparation of Compound 55 with the exception that 2 equivalents of bromine was used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455658B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-4cbb285ef03145899b6a62dfe55242cb |
| Source note | uspto-grants-2013_06 |