N-(5-(7-Bromobenzo[d][1,3]dioxol-5-yl)-4-methylthiazol-2-yl)-2,6-difluorobenzamide → N-(5-(Benzo[d][1,3]dioxol-5-yl)-4-methylthiazol-2-yl)-2,6-difluorobenzamide

Participants

Reaction Steps

A mixture of Compound 56 (50 mg) and 10% Pd/C (10 mg) in EtOH (2.0 mL) was stirred under an atmosphere of hydrogen gas overnight. The mixture was filtered through a short plug of celite. The filtrate was concentrated under reduced pressure to give Compound 57 (37 mg).

Provenance & Evidence