HCID 86633501, compound → HCID 86633500, compound

HRID 1255223Notes

Reaction equation

HRID 1255223 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:10](Br)([F:12])[F:11])=[C:6]([CH:9]=1)[CH:7]=[O:8].[OH:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[C:21]1[N:26]=[C:25]([N:27]2[C:31]([C:32]([F:35])([F:34])[F:33])=[C:30]([C:36]([O:38][CH2:39][CH3:40])=[O:37])[CH:29]=[N:28]2)[CH:24]=[CH:23][CH:22]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:10]([F:12])([F:11])[O:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[C:21]2[N:26]=[C:25]([N:27]3[C:31]([C:32]([F:35])([F:34])[F:33])=[C:30]([C:36]([O:38][CH2:39][CH3:40])=[O:37])[CH:29]=[N:28]3)[CH:24]=[CH:23][CH:22]=2)=[C:6]([CH:7]=[O:8])[CH:9]=1

Participants

3

Reactant 2

HCID 86633501HCID 86633501, compoundHCID 136298134Ethyl 1-[6-(2-hydroxylphenyl)pyridine-2-yl]-5-trifluoromethyl-1H-pyrazole-4-carboxylate

Product 1

HCID 86633500HCID 86633500, compound

Procedure

By analogy to Example 300 Step A, reaction of the title compound from Example 302 Step C with the title compound from Example 1 Step B provided the title compound: LCMS m/z 592.5 [M−F]+.

Sources & evidence

ORD record
ord-13a84c8da2b643fdae15f164d33c6da1
Source dataset
uspto-grants-2013_06
Patent number
US08455638B2

Reaction notes

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