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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1255267Generated: November 1, 2026

3-(3-(Hydroxymethyl)phenyl)propan-1-ol → 3-(4-(tert-Butyldimethylsilyloxy)butyl)benzaldehyde

https://huagongshe.com/reaction/1255267

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-(Hydroxymethyl)phenyl)propan-1-olHCID 55267680—
Reactant(3-(4-(tert-Butyldimethylsilyloxy)butyl)phenyl)methanolHCID 58168515—
Product3-(4-(tert-Butyldimethylsilyloxy)butyl)benzaldehydeHCID 58168615—

Reaction Steps

Prepared by the method of Aromatic Intermediate 18, step c using (3-(4-(tert-butyldimethylsilyloxy)butyl)phenyl)methanol [Aromatic Intermediate 19, step b] (0.72 g) in place of 3-(3-(hydroxymethyl)phenyl)propan-1-ol. Yield 0.64 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455483B2
Source datasetuspto-grants-2013_06
ORD IDord-9bf643a3914749d6b291cb777cc668b6
Source noteuspto-grants-2013_06