8-Amino-1-(2-methoxy-ethyl)-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one → (2-{5-Chloro-2-[1-(2-methoxy-ethyl)-5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino]-pyrimidin-4-ylamino}-phenoxy)-acetonitrile
Reaction equation
[Cl:20][c:21]1[n:22][cH:23][c:24]([Cl:38])[c:25]([NH:27][c:28]2[c:29]([O:30][CH2:31][C:32]#[N:33])[cH:34][cH:35][cH:36][cH:37]2)[n:26]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[N:7]([CH2:15][CH2:16][O:17][CH3:18])[C:8](=[O:14])[CH2:9][CH2:10][C:11]2([CH3:12])[CH3:13]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[N:7]([CH2:15][CH2:16][O:17][CH3:18])[C:8](=[O:14])[CH2:9][CH2:10][C:11]2([CH3:12])[CH3:13])[c:21]1[n:22][cH:23][c:24]([Cl:38])[c:25]([NH:27][c:28]2[c:29]([O:30][CH2:31][C:32]#[N:33])[cH:34][cH:35][cH:36][cH:37]2)[n:26]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-40951b6357cc44f6b8a84e1c389d0db8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…