HCID 86650155, compound → HCID 86650134, compound

HRID 1255392Notes

Reaction equation

HRID 1255392 reaction equation
FC(C1N=C2C(C=C(C(O)=O)C(C(F)(F)F)=N2)=CC=1F)(F)C.FC([C:27]1[N:36]=[C:35]2[C:30]([CH:31]=[C:32]([C:41]([CH:43]3[C:48](=[O:49])[CH2:47][CH2:46][CH2:45][C:44]3=[O:50])=[O:42])[C:33]([C:37]([F:40])([F:39])[F:38])=[N:34]2)=[CH:29][C:28]=1F)(F)C>>[F:40][C:37]([F:38])([F:39])[C:33]1[C:32]([C:41]([CH:43]2[C:48](=[O:49])[CH2:47][CH2:46][CH2:45][C:44]2=[O:50])=[O:42])=[CH:31][C:30]2[C:35](=[N:36][CH:27]=[CH:28][CH:29]=2)[N:34]=1

Participants

3

Reactant 2

HCID 86650155HCID 86650155, compoundHCID 86761876HCID 86761876, compound

Product 1

HCID 86650134HCID 86650134, compound

Procedure

From 7-(1,1-difluoroethyl)-6-fluoro-2-trifluoromethyl-[1,8]-naphthyridine-3-carboxylic acid, 2-[7-(1,1-difluoroethyl)-6-fluoro-2-trifluoromethyl-[1,8]-naphthyridine-3-carbony]-cyclohexane-1,3-dione, yellow solid, 1H NMR (CDCl3) δ: 8.08 (1H, s), 7.95 (1H, d), 2.85 (2H, broad s), 2.42 (2H, broad s), 2.23 (3H, t), (2H, quintet). Molecular ion: (MH)+418.

Sources & evidence

ORD record
ord-d177263d743c4520a300199c4e931d9d
Source dataset
uspto-grants-2013_06
Patent number
US08461083B2

Reaction notes

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